Tools for ADME/Tox has been produced with the preclinical or ADMET drug discovery researcher in mind. Each index details the metabolising enzyme with the relevant substrate, metabolite, inhibitor or inducer. For quick reference, substrates and metabolites for any single metabolism enzyme have been aligned on opposing pages of the index section. Each metabolism enzyme has relevant substrates, metabolites, inducers and inhibitors relevant to the enzyme listed with reference to FDA Drug Development and Drug interactions: Table of Substrates, Inhibitors and Inducers.
The catalogue listing includes quick reference guides for labelled and fluorescent products which are key tools to the ADMET researcher. |