|Regardless of their origin there is a very real risk of cell cross-contamination. This risk increases in both research groups who maintain immortal cells over a number of years and those who do not source their cells directly from a recognised repository like ATCC®.
A growing number of high impact journals including biotechniques and Cancer Research now require information on the authentication of any cell line used in the study prior to reviewing a submitted paper. There is increasing evidence that research bodies will implement cell line authentication as part of their grant application review process. The trend which seems to be emerging is that a cell line used in a submission must have been either acquired from a reputable repository, such as ATCC, or been authenticated within the 6 months prior to article submission.
One of the most commonly accepted cell authentication techniques is short tandem repeat (STR) profiling which LGC, as the largest privately owned forensic science service provider in the UK, is highly experienced. In addition, LGC delivers state-of-the-art DNA familial testing services in Germany operating in both Berlin and Cologne.
LGC Standards experience in STR profiling through our forensic division and cell biology expertise gained through our collaboration with ATCC enables the provision of a fully supported cell line authentication program.
LGC Standards is pleased to now offer STR profiling and a range of cell line authentication services designed to support your research results. LGC Standards genotyping laboratories are equipped with state of the art equipment and are able to generate genotypes from a variety of different sample types including cell pellets, frozen cell aliquots or extracted genomic DNA. We are also able to offer genotyping using a number of different technologies.
Cell line authentication service overview
Cell line authentication technical overview
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