2,5-Anhydro-2,5-imino-D-glucitol
Product Code
TRC-A648300-5MG
CAS Number
Product Format
Neat
Molecular Formula
C6 H13 N O4
Molecular Weight
163.17
Product Categories
Product Type
Bioactive Small MoleculeShare product
- Product Name: 2,5-Anhydro-2,5-imino-D-glucitol
- Product Code: TRC-A648300-5MG
- CAS Number: 132295-44-4
- Brand: TRC
Documentation
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Product Information
Chemical Data
Analyte Name
2,5-Anhydro-2,5-imino-D-glucitol
CAS Number
132295-44-4
Molecular Formula
C6 H13 N O4
Molecular Weight
163.17
Accurate Mass
163.0845
SMILES
OC[C@@H]1N[C@H](CO)[C@@H](O)[C@@H]1O
InChI
InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1
IUPAC
(2R,3R,4R,5S)-2,5-bis(hydroxymethyl)pyrrolidine-3,4-diol
Product Data
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Format
Neat
Product Description
Many pyrrolidines are powerful inhibitors of glycohydrolases, enzymes responsible for cleavage of glycosidic bonds, glycoprotein processing and the gastrointestinal breakdown of dietary carbohydrates. These compounds are charged at physiological pH and are believed to associate with acidic amino acids at the active site. Inhibition of glycohydrolases could be of therapeutic value for the treatment of viral infections, cancer, diabetes, and obesity.
References: Fellows, L.E., et al.: J. Chem. Brit., 287, (1987), Elbein, A.D.: Annu. Rev. Biochem., 56, 497 (1987), Fleet, G.W., et al.: J. Chem. Brit., 287, (1989) Baxter, E.W., et al.: J. Org. Chem., 59, 3175 (1994); Tyms, A.S. et al. Lancet 1025, (1987); Spearman, M.A. et al. Expt. Cell Res. 168, 116 (1987); Horii, S. et al. J. Med. Chem. 29, 1038 (1986).
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