Drug testing is extremely accurate and reliable when all aspects of the testing process are carried out correctly. However, if poor procedures and inadequate testing methods are utilised, the information obtained may be very misleading and inaccurate. To minimise this risk, laboratories should perform routine quality-control tests and participate in suitable PT/EQA schemes.

The AXIO Proficiency Testing Drugs in Oral Fluid Scheme (DOF) provides performance assessment for laboratories and clinics that provide analytical services for drugs in oral fluid. The samples are provided as real human oral fluid. Advances in technology have enabled oral fluid testing for the presence of many drugs; the oral fluid collection is often less invasive, relatively easy to perform, and, in forensic situations, can be achieved under close supervision to prevent adulteration or substitution of the samples.

The operation of our AXIO DOF scheme is supported by an Advisory Group consisting of members of the professional bodies, scheme participants, and others experienced in the field. The scheme reports on the performance of U.K. participants (who have clinical responsibilities) to the National Quality Assurance Advisory Panels for Chemical Pathology.