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LGC Standards extends range of GMO standards to meet EC recommendations

Date:02 June 2011

LGC Standards, Europe?s leading supplier of reference materials, is pleased to announce that a new range of genetically modified (GM) certified reference materials (CRMs) are now available. Produced by the Institute for Reference Materials and Measurements (IRMM), these CRMs meet the recommendations from the European Commission.

Recommendation (EC) No. 787/2004 suggests that results of the content of genetically modified organisms (GMO) in food and feed should be expressed as copy number ratios. IRMM has released a string of plasmidic DNA materials: ERM-AD413, ERM-AD415, ERM-AD425 and ERM-AD427 intended as calibrants for the determination of GMO copy number ratios for GM varieties authorised in Europe. The materials have been processed and certified according to ISO Guide 34 by the Institute for Reference Materials and Measurements (IRMM), which is one of the institutes of the European Commission's Joint Research Centre.

In addition to these new plasmidic DNA certified reference materials, certified values for copy number ratios have been assigned in addition to the existing certified mass fractions to a selection of existing matrix CRMs to allow laboratories to implement this recommendation.


CRM Description
ERM-BF413ek MON 810 maize powder (level 3)
ERM-BF415e NK603 maize (level 4)
ERM-BF425c Soya 356043 (level 2)
ERM-BF427c 98140 maize (level 2)

With the copy number certification (and the matching plasmidic calibrant) LGC Standards and IRMM are supporting analysts wishing to apply the Commission recommendation with quality assurance and measurement tools to do so in a controlled manner.

Jane Firth, Sector Manager at LGC Standards, said: ?Calibration and analysis of matrix materials for quality control are both critical stages in ensuring the ongoing performance of an analytical method. These GMO standards provide the analyst with sets consisting of a matrix CRM for quality control and a plasmid DNA CRM suitable for calibration. Together with the event-specific PCR method, this forms a reference system for the expression of the measured GM quantity in copy number ratios as described in the current EC Recommendation.?

LGC Standards supplies the complete range of GMO certified reference materials from IRMM including maize, cotton seed and sugar beet, which can be used as calibrants for DNA-based methods. Please contact askus@lgcstandards.com for further information.


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Notes to editors

About LGC Standards
LGC Standards (www.lgcstandards.com) provides products and services to improve measurement and quality control within the laboratory, and is part of LGC, whose LGC Science & Technology Division acts as the UK National Measurement Institute for chemical and bioanalytical measurements. LGC Standards supplies over 100,000 products, including reference materials, pharmaceutical impurity reference standards (produced under ISO Guide 34 accreditation), biological standards and reagents, and proficiency testing. LGC Standards is headquartered in Teddington, Middlesex, UK. Its global centre for excellence in proficiency testing is located in Bury (Greater Manchester). LGC Standards has offices in France, Germany, Italy, Poland, Spain, Sweden, China, Russia, United Arab Emirates and the UK, a joint venture presence in India, and representatives in Brazil, Bulgaria, Czech Republic, Finland, Hungary, Ireland, the Netherlands, Romania, Turkey and the US.

About LGC
LGC (www.lgcgroup.com) is an international science-based company and market leader in analytical, forensic and diagnostic services and reference standards. LGC operates in a variety of markets which underpin the safety, health and security of the public and the regulation of industry, for both public and private sector clients.
LGC operates internationally through four divisions - LGC Forensics, LGC Genomics, LGC Standards and LGC Science & Technology. The latter includes specialist laboratories delivering contracts for the Department for Business, Innovation and Skills (BIS) and supports LGC's designated role as the UK's National Measurement Institute for chemical and bioanalytical measurement.

Our operations are extensively accredited to international quality standards such as ISO 17025. With headquarters in Teddington, South West London, the LGC Group employs ca 1,400 staff in 29 laboratories and centres globally. Privatised in 1996 and now majority-owned by funds managed by Bridgepoint, LGC was founded almost 170 years ago as the Laboratory of the Government Chemist - a statutory function maintained by LGC today.

For further information contact:
Amanda Russell
Marketing Manager
LGC Standards
Queens Road
TW11 0LY
Tel: +44 (0)20 8943 7412
Fax: +44 (0)20 8943 7009
Email: amanda.russell@lgcstandards.com

Gavin Dallas
Press & Communications Officer
Queens Road
TW11 0LY
Tel: +44 (0)20 8943 8491
Fax: +44 (0)20 8943 2767
Email: gavin.dallas@lgcgroup.com



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