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LGC Standards offers new reference materials to improve stilbene detection

Date:09 February 2012

LGC Standards, Europe?s leading supplier of reference materials, has introduced two new reference materials for stilbenes in bovine urine, expanding further its range from the Institute for Reference Materials and Measurements (IRMM).

Collectively known as stilbenes, diethylstilbestrol (DES), hexestrol (HEX) and dienestrol (DE) are oestrogenic hormones that are prohibited worldwide for use in food-producing livestock. Their use as growth promoting agents in veal and calf production is banned and the compounds form part of the national sampling and monitoring plans as stipulated by European legislation (Council Directive 96/23/EC).

Available from LGC Standards, the two reference materials comprising ERM-BB389 (DES, DE, HEX in bovine urine) and ERM-BB386 (stilbene blank material) are preparations of new materials to replace the stilbene-containing CRMs BCR-389 (DES), BCR-390 (DE), and BCR-391 (HEX) and the respective blank materials BCR-386, BCR-387, BCR-388.

Stilbene concentrations have been lowered from 13 - 34 ?g/kg in the previous materials to 1 - 6 ?g/kg per substance in the new CRMs, thereby providing improved confidence in the high sensitivity detection of these banned substances. In addition, the new unit size allows for more replicates per unit to be taken.


These new, improved reference materials are intended to be used for method validation purposes (trueness estimation) and method performance control. The certified value for ERM-BB389 amounts to 1.1 ± 0.5 ?g/kg (DES), 5.5 ± 1.4 ?g/kg (DE), 6.1 ± 0.9 ?g/kg (HEX) and is based on an inter-laboratory characterisation study; the uncertainty value contains contributions from the characterisation study, and the homogeneity and stability assessment. The values are traceable to the International System of Units (SI) and the materials have been processed and certified in accordance to ISO Guides 34 and 35.

For further information on these new stilbene reference materials, contact your local LGC Standards sales office, or email: askus@lgcstandards.com. Customers within the UK can place an order through the LGC webshop (www.lgcstandards.com).


- Ends -



Notes to editors

About LGC Standards

LGC Standards provides products and services to improve measurement and quality control within the laboratory, and is part of LGC, whose LGC Science & Technology Division acts as the UK National Measurement Institute for chemical and bioanalytical measurements. LGC Standards supplies over 100,000 products, including reference materials, pharmaceutical impurity reference standards (produced under ISO Guide 34 accreditation), biological standards and reagents, and proficiency testing. LGC Standards is headquartered in Teddington, Middlesex, UK. Its global centre for excellence in proficiency testing is located in Bury (Greater Manchester). LGC Standards has offices in France, Germany, Italy, Poland, South Africa, Spain, Sweden, China, Russia, United Arab Emirates and the UK, a joint venture presence in India, and representatives in Brazil, Bulgaria, Czech Republic, Finland, Hungary, Ireland, the Netherlands, Romania, Turkey and the US.

About LGC

LGC (www.lgcgroup.com) is the international science-based company and market leader in analytical, forensic, biotechnology and diagnostic services, as well as diagnostic products, proficiency testing and reference standards. LGC operates in a variety of international markets which underpin the safety, health and security of the public and the regulation of industry, for both public and private sector clients.

LGC has four divisions - LGC Forensics, LGC Genomics, LGC Standards and LGC Science & Technology. The latter includes specialist laboratories delivering contracts for the Department for Business, Innovation and Skills (BIS) and supports LGC's designated role as the UK's National Measurement Institute for chemical and bioanalytical measurement.

Our operations are extensively accredited to international quality standards such as ISO/IEC 17025. With headquarters in Teddington, South West London, the LGC Group employs over 1,600 staff in 36 laboratories and centres globally. Privatised in 1996 and now majority-owned by funds managed by Bridgepoint, LGC was founded almost 170 years ago as the Laboratory of the Government Chemist - a statutory function maintained by LGC today.

For further information contact:


Jane Firth

Business Sector Manager

LGC Standards, Queens Road, Teddington, Middlesex, TW11 0LY, UK

Tel: +44 (0)20 8943 7323

Fax: +44 (0)20 8943 7009

Email: jane.firth@lgcgroup.com

Web: www.lgcstandards.com

Webshop: www.lgcstandards.com

Gavin Dallas

Communications / Press Officer

LGC, Queens Road, Teddington, Middlesex, TW11 0LY, UK

Tel: +44 (0)20 8943 7000

Fax: +44 (0)20 8943 2767

Direct Line: +44 (0)20 8943 8491

Email: gavin.dallas@lgcgroup.com

Web: www.lgcgroup.com

Twitter: www.twitter.com/LGCGroup

Blog: www.blog.lgcgroup.com

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