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Product Overview

Product Code

TRC-T887825

CAS Number

1797133-13-1

Product Format

Neat

Molecular Formula

C40H35ClN6

Molecular Weight

635.21

Product Categories

TRC, Antihypertensives, API Reference Standards & Research Materials

Product Type

API

Documentation

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Product Information

Chemical Data

Analyte Name

N-Trityl-deshydroxymethyl Losartan

CAS Number

1797133-13-1

Molecular Formula

C40H35ClN6

Molecular Weight

635.21

Accurate Mass

634.2612

SMILES

CCCCc1nc(Cl)cn1Cc2ccc(cc2)c3ccccc3c4nnn(n4)C(c5ccccc5)(c6ccccc6)c7ccccc7

InChI

InChI=1S/C40H35ClN6/c1-2-3-23-38-42-37(41)29-46(38)28-30-24-26-31(27-25-30)35-21-13-14-22-36(35)39-43-45-47(44-39)40(32-15-7-4-8-16-32,33-17-9-5-10-18-33)34-19-11-6-12-20-34/h4-22,24-27,29H,2-3,23,28H2,1H3

IUPAC

5-[2-[4-[(2-butyl-4-chloroimidazol-1-yl)methyl]phenyl]phenyl]-2-trityltetrazole

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Product Description

N-Trityl-deshydroxymethyl Losartan is an intermediate in the preparation of Losartan (L470470) impurities which is a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.

References: Chiu, T.A., et al.: J. Pharmacol. Exp. Ther., 252, 711 (1990); McIntyre, M., et al.: Pharmacol. Ther., 74, 181 (1997); Pitt, B., et al.: Lancet, 355, 1582 (2000);

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