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Product Overview

Product Code

TRC-B684250

CAS Number

26139-15-1

Product Format

Neat

Molecular Formula

C3 H7 Br O2 S2

Molecular Weight

219.12

Product Categories

GABA receptors, TRC, Neurotransmission, Alzheimer's, Depression, Epilepsy, Memory, Learning and Cognition, Parkinson's, Schizophrenia, Addiction, Sleep, Stress and Anxiety, Stroke, Pain and Inflammation

Product Information

Chemical Data

Analyte Name

2-Bromoethyl Methanethiosulfonate

CAS Number

26139-15-1

Molecular Formula

C3 H7 Br O2 S2

Molecular Weight

219.12

Accurate Mass

217.9071

SMILES

CS(=O)(=O)SCCBr

InChI

InChI=1S/C3H7BrO2S2/c1-8(5,6)7-3-2-4/h2-3H2,1H3

IUPAC

1-bromo-2-methylsulfonylsulfanylethane

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Product Description

Reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease. Useful for mapping the pore-lining regions of the ryanodine receptor.

References: Yang, N. et al.: Neuron, 16, 113 (1996), Kuner, T. et al.: Neuron, 17, 343 (1996), Holmgren, M. et al: Neuropharmacology, 35, 797 (1996) Chahine, M. et al.: Biochemical & Biophysical Res. Commun., 233, 606 (1997), Ehrlich, B.E., et al.: J. Gen. Physiol., 109, 255 (1997), Rassendren, F., et al.: The EMBO Journal, 16, 3446 (1997), Egan, T.M., et al.: The Journal of Neuroscience, 18(7), 2350 (1998), Lin, C.-W. and Tsung-Yu, C.: J. Gen. Physiol., 116, 535 (2000)

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