Product Code

TRC-M425000

CAS Number

118427-55-7

Product Format

Neat

Molecular Formula

C27 H33 Cl N O2 S . Na

Molecular Weight

494.06

Product Categories

TRC, Enzyme inhibitors, Bioactive small molecules, Angiogenesis, Leukotriene, Neuroinflammation Research Chemicals & Analytical Standards, Neuroinflammation Research Chemicals & Analytical Standards, Pain and Inflammation, Chiral catalysts, ligands, & reagents

Product Type

Synthesis Tools

Alternate CAS Number

Free form: 118414-82-7

Price and availability

48-hour USA dispatch time

Freight restricted.

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Product Information

Chemical Data

Analyte Name

MK-886 sodium salt

CAS Number

118427-55-7

Molecular Formula

C27 H33 Cl N O2 S . Na

Molecular Weight

494.06

Accurate Mass

493.1818

Flash Point

SMILES

[Na+].CC(C)c1ccc2c(c1)c(SC(C)(C)C)c(CC(C)(C)C(=O)[O-])n2Cc3ccc(Cl)cc3

InChI

InChI=1S/C27H34ClNO2S.Na/c1-17(2)19-10-13-22-21(14-19)24(32-26(3,4)5)23(15-27(6,7)25(30)31)29(22)16-18-8-11-20(28)12-9-18;/h8-14,17H,15-16H2,1-7H3,(H,30,31);/q;+1/p-1

IUPAC

sodium;3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoate

Alternate CAS Number

Free form: 118414-82-7

Product Data

Storage Temperature

+20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Product Description

MK-886 is a leukotriene inhibitor. MK-886 and Celecoxib have an inhibitory effect on the growth of pancreatic cancer cell line SW1990 and angiogenesis.

References: Dixon, R.A.F., et al.: Nature, 343, 282 (1990), Kargman, S., et al.: J. Biol. Chem., 266, 23745 (1991), Ford-Hutchinson, A.W., et al.: Trends Pharmacol. Sci., 12, 63 (1991),

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