Do you want to proceed?

{{requestQuote.productName}}; {{requestQuote.displayProductCode}}

Phone Number *

Shipping address *

Shipping address

Not the right shipping address?

Organisation name *

Address line 1 *

Address line 2

Country *

City *

Select from existing

Billing address *

Organisation name *

Address line 1 *

Address line 2

Country *

City *

Desired delivery date

Exact weight required

Additional requirements

Alternatives acceptable if checked, we will discuss alternatives with you if we are unable to fill your request from existing stock

Multiple lots acceptable if checked, the order may be filled from multiple different lots

Recurring need check to inform us that you intend to order again. Leave unchecked if this is a one-time order

Cancel

Thank you

We will respond to your enquiry shortly.

Something went wrong, please try again later.

Product Overview

Product Code

TRC-M425000

CAS Number

118427-55-7

Product Format

Neat

Molecular Formula

C27 H33 Cl N O2 S . Na

Molecular Weight

494.06

Product Categories

TRC, Enzyme inhibitors, Bioactive small molecules, Angiogenesis, Leukotriene, Neuroinflammation Research Chemicals & Analytical Standards, Neuroinflammation Research Chemicals & Analytical Standards, Pain and Inflammation, Chiral catalysts, ligands, & reagents

Product Type

Synthesis Tools

Alternate CAS Number

Free form: 118414-82-7

Documentation

Where shall we send your requested CoA?

Part number: {{ coaPopupData.packSize.code }}

LGC will use your email address only for the purposes of providing the requested document.
For information about our data processing activities, please visit our Privacy Notice.

Where shall we send your requested CoA?

Enter your email address and we'll email you the relevant CoA for lots:
{{ coaPopupData.packSize.coaSelectedLotNumbers }}

By entering your email address, you confirm that you give your consent to LGC to share information in connection with the product(s) above and other similar products from time to time. LGC will process your personal data in accordance with all applicable data protection rules and regulations. For information relating to LGC's data processing activities, please visit our Privacy Policy below (see footer).

Thank you

We will be sending the CoA to your email address {{ coaEmailPopupData.userEmail }}

Thank you

Your request has been sent to our sales team to process.

Where shall we send your requested SDS?

Part number: {{ sdsPopupData.packSize.code }}

LGC will use your email address only for the purposes of providing the requested document.
For information about our data processing activities, please visit our Privacy Notice.

Thank you

Your request has been sent to our sales team to process.

Product Information

Chemical Data

Analyte Name

MK-886 sodium salt

CAS Number

118427-55-7

Molecular Formula

C27 H33 Cl N O2 S . Na

Molecular Weight

494.06

Accurate Mass

493.1818

Flash Point

SMILES

[Na+].CC(C)c1ccc2c(c1)c(SC(C)(C)C)c(CC(C)(C)C(=O)[O-])n2Cc3ccc(Cl)cc3

InChI

InChI=1S/C27H34ClNO2S.Na/c1-17(2)19-10-13-22-21(14-19)24(32-26(3,4)5)23(15-27(6,7)25(30)31)29(22)16-18-8-11-20(28)12-9-18;/h8-14,17H,15-16H2,1-7H3,(H,30,31);/q;+1/p-1

IUPAC

sodium;3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoate

Alternate CAS Number

Free form: 118414-82-7

Product Data

Storage Temperature

+20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Product Description

MK-886 is a leukotriene inhibitor. MK-886 and Celecoxib have an inhibitory effect on the growth of pancreatic cancer cell line SW1990 and angiogenesis.

References: Dixon, R.A.F., et al.: Nature, 343, 282 (1990), Kargman, S., et al.: J. Biol. Chem., 266, 23745 (1991), Ford-Hutchinson, A.W., et al.: Trends Pharmacol. Sci., 12, 63 (1991),

Thank you

{{entry.product.manufacturer}}

{{entry.product.name}}

Thank you

Product Overview

Documentation

Product Information

Chemical Data

Product Data

Product Description

Product citations

Thank you

{{entry.product.manufacturer}}

{{entry.product.name}}

MK-886 Sodium Salt

Thank you

Share product

Product Overview

Documentation

Product Information

Chemical Data

Product Data

Product Description

Product citations

{{title}}

Thank you