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Product Overview

Product Code

TRC-L470505

CAS Number

114798-36-6

EP Description

Losartan EP Impurity K

USP Description

Losartan USP Related Compound C

Product Format

Neat

Molecular Formula

C22 H21 Cl N6 O

Molecular Weight

420.89

API Family

Losartan Potassium

Product Categories

TRC, Impurity Reference Materials

Product Type

Impurity, Metabolite

Documentation

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Product Information

Chemical Data

Analyte Name

Losartan Carboxaldehyde

CAS Number

114798-36-6

Molecular Formula

C22 H21 Cl N6 O

Molecular Weight

420.89

Accurate Mass

420.1465

SMILES

CCCCc1nc(Cl)c(C=O)n1Cc2ccc(cc2)c3ccccc3c4nnn[nH]4

InChI

InChI=1S/C22H21ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,14H,2-3,8,13H2,1H3,(H,25,26,27,28)

IUPAC

2-butyl-5-chloro-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carbaldehyde

Product Data

Storage Temperature

+4°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

API Family

Losartan Potassium

Product Description

A metabolite of Losartan. An intermediate in the synthesis of the EXP 3174. Losartan EP Impurity K. Losartan USP Related Compound C.

References: Pieter, B.M.W.M., et al.: Hypertension, Supp. III, 18, 5, (1991), Chang, L.L., et al.: J. Med. Chem., 36, 2558 (1993)

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