Product Code

TRC-T797150

CAS Number

134962-48-4

Product Format

Neat

Molecular Formula

C21 H44 N O2 . Cl

Molecular Weight

378.03

Product Categories

TRC, API Reference Standards & Research Materials

Product Type

API

Price and availability

48-hour USA dispatch time

Freight restricted.

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Product Information

Chemical Data

Analyte Name

D-erythro-N,N,N-Trimethylsphingosine Chloride

CAS Number

134962-48-4

Molecular Formula

C21 H44 N O2 . Cl

Molecular Weight

378.03

Accurate Mass

377.3061

SMILES

[Cl-].CCCCCCCCCCCCC\C=C\[C@H](O)[C@@H](CO)[N+](C)(C)C

InChI

InChI=1S/C21H44NO2.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21(24)20(19-23)22(2,3)4;/h17-18,20-21,23-24H,5-16,19H2,1-4H3;1H/q+1;/p-1/b18-17+;/t20-,21+;/m1./s1

IUPAC

[(E,2R,3S)-1,3-dihydroxyoctadec-4-en-2-yl]-trimethylazanium;chloride

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Product Description

Has an inhibitory effect via blocking of transmembrane signaling on the growth of various human tumor cell lines in vitro as well as in vivo in nu/nu mice. A potent and effective cardioprotective agent that inhibits leukocyte-endothelial cell interactions and preserves cardiac contractile function and coronary perfusion following myocardial ischemia and reperfusion.

References: Handa, K., et al.: Biochemistry, 30, 50, 11684 (1991), Endo, K., et al.: Cancer Research, 51, 1613 (1991), Park, Y.S., et al.: Cancer Research, 54, 2213 (1994), Kennedy, S.D., et al.: Am. J. Clin. Pathol., 107, 1, 99 (1997), Campbell, B., et al: Cardivasc. Res., 39, 2, 393 (1998),

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D-erythro-N,N,N-Trimethylsphingosine Chloride

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