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Chloroquine

Product Code

TRC-C380318

CAS Number

54-05-7

Product Format

Neat

Molecular Formula

C18 H26 Cl N3

Molecular Weight

319.87

API Family

Chloroquine

Product Type

API

Price and availability

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Documentation

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Product Information

Product Notes

Chloroquine, used in the treatment of malaria and MDR-strains, is an endosomal pH regulator, which in vitro has shown inhibition of the viral replication of SARS-COV. Addition of chloroquine to infected cultures could be delayed up to 5h post-infection without an important drop in antiviral activity (3). 

 

References
[1] Laufer, M. et al.: PLoS One., 7, e42284 (2012).

[2] Hangartner, S. et al.: Drug Test. ANal., 5, 777 (2013).

[3] Keyaerts, E., Vijgen, L., Maes, P., Neyts, J. and Van Ranst, M. In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine, Biochemical and Biophysical Research Communications, 323(1), 264-268 (2004) [Online]. Available at: https://www.sciencedirect.com/science/article/pii/S0006291X0401839X.

Product Data

Analyte Name

Chloroquine

CAS Number

54-05-7

Molecular Formula

C18 H26 Cl N3

Molecular Weight

319.87

Accurate Mass

319.1815

SMILES

CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12

InChI

InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)

IUPAC

4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine

Storage & Transport Information

Storage Temperature

+4°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Attributes

Product Type

API

Product Format

Neat

API Family

Chloroquine

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