D-erythro-Sphingosine (synthetic)
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Product Overview
Product Code
TRC-S681000
CAS Number
Product Format
Neat
Molecular Formula
C18 H37 N O2
Molecular Weight
299.49
Product Categories
Product Type
Synthesis ToolsPurity
>95% (HPLC)
Documentation
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Product Information
Chemical Data
Analyte Name
D-erythro-Sphingosine
CAS Number
123-78-4
Molecular Formula
C18 H37 N O2
Molecular Weight
299.49
Accurate Mass
299.2824
SMILES
CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)CO
InChI
InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18+/m0/s1
IUPAC
(E,2S,3R)-2-aminooctadec-4-ene-1,3-diol
Product Data
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Format
Neat
Purity
>95% (HPLC)
Product Description
Selective inhibitor of protein kinase C activity and phorbol dibutyrate binding in vitro in human platelets; does not inhibit protein kinase A or myosin light chain kinase; inhibits calmodulin-dependent enzymes; natural isomer of sphingosine.
References: Yoon, C., et al.: Mol. Cancer Res., 7, 361 (2009), Giussani, P., et al.: J. Biol. Chem., 284, 5088 (2009), Chen-Quay, S., et al.: J. Pharm. Sci., 98, 606 (2009), Satoh, Y., et al.: J. Biochem., 145, 31 (2009),