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Product Overview

Product Code

TRC-S688700

CAS Number

149647-78-9

Product Format

Neat

Molecular Formula

C14 H20 N2 O3

Molecular Weight

264.32

API Family

Vorinostat, Suberoylanilide Hydroxamic Acid

Product Categories

TRC, Enzyme inhibitors, API Reference Standards & Research Materials, Angiogenesis, Histone and related compounds, Huntington's, Memory, Learning and Cognition, Pharmaceutical Toxicology Reference Materials

Product Type

API

Purity

>95% (HPLC)

Documentation

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Product Information

Chemical Data

Analyte Name

Suberoylanilide Hydroxamic Acid

CAS Number

149647-78-9

Molecular Formula

C14 H20 N2 O3

Molecular Weight

264.32

Accurate Mass

264.1474

SMILES

ONC(=O)CCCCCCC(=O)Nc1ccccc1

InChI

InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)

IUPAC

N'-hydroxy-N-phenyloctanediamide

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Type

API

Product Format

Neat

API Family

Vorinostat; Suberoylanilide Hydroxamic Acid

Purity

>95% (HPLC)

Product Description

Suberoylanilide Hydroxamic Acid is a potent, selective, cell permeable histone deacetylase inhibitor (HDAC). Suberoylanilide Hydroxamic Acid displays anti-angiogenic activity by interfering with VEGF signaling in human umbilical vein endothelial cells (HUVECs). Suberoylanilide Hydroxamic Acid induces differentiation in uman breast cancer cells. Potent Histone deacetylase inhibitor.

References: Richon, V.M., et al.: Proc. Natl. Acad.Sci. USA, 95, 3003 (1988), Munster, P.N., et al.: Cancer Res., 61, 8492 (2001), Deroanne, C.F., et al.: Oncogene, 21, 247 (2002),

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