Name: rac erythro-9-(2-Hydroxy-3-nonyl)adenine Hydrochloride Salt
Brand: TRC
SKU: TRC-H825550-1MG

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Product Overview

Product Code

TRC-H825550-1MG

CAS Number

58337-38-5

Product Format

Neat

Molecular Formula

C14 H23 N5 O . Cl H

Molecular Weight

313.83

Product Categories

Enzyme inhibitors, TRC, Bioactive small molecules, Enzyme inhibitors, Adenosine receptors, Phosphodiesterase, Huntington's, Memory, Learning and Cognition, Parkinson's, Schizophrenia, Sleep, Stress and Anxiety, Stroke

Product Type

Bioactive Small Molecule

Alternate CAS Number

Free amine: 51350-19-7

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Product Information

Chemical Data

Analyte Name

rac erythro-9-(2-Hydroxy-3-nonyl)adenine, Hydrochloride

CAS Number

58337-38-5

Molecular Formula

C14 H23 N5 O . Cl H

Molecular Weight

313.83

Accurate Mass

313.1669

SMILES

Cl.CCCCCC[C@H]([C@H](C)O)n1cnc2c(N)ncnc12

InChI

InChI=1S/C14H23N5O.ClH/c1-3-4-5-6-7-11(10(2)20)19-9-18-12-13(15)16-8-17-14(12)19;/h8-11,20H,3-7H2,1-2H3,(H2,15,16,17);1H/t10-,11+;/m0./s1

IUPAC

(2S,3R)-3-(6-aminopurin-9-yl)nonan-2-ol;hydrochloride

Alternate CAS Number

Free amine: 51350-19-7

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Product Description

A potent inhibitor of phosphodiesterase II (PDE II) (IC50=800nM). Does not inhibit other PDE isozymes (IC50>100uM). Inhibits the retrograde transport motor, dynein. Also inhibits adenosine deaminase (Ki=4nM). Potent PDE-2 inhibitor.

References: Lorbar, M., et al.: J. Mol. Cell. Cardiol., 31, 401 (1999), Verde, I., et al.: Br. J. Pharmacol., 127, 65 (1999),

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