In 2025, LGC Standards took its manufacturing expertise and thought leadership to another level. Boosted by the opening of our state-of-the-art, 203,000 sq. ft. Organic Chemistry Centre of Excellence in Vaughan, Ontario, we released 2,000 new products to meet emerging global needs – including more than 130 PFAS standards, 21 new API reference materials, and a revolutionary new range of microplastic reference materials. We also brought you over 20 thought leadership publications – including white papers, guides, technical posters, and ebooks – as well as seven expert-led webinars watched by thousands of scientists around the globe. In case you missed them, here’s a quick recap of our most-watched, and most-read, releases from 2025.
1. Nitrosamine formation in pharmaceuticals – pathways and prevention strategies.
This practical guide reviews current understanding of small molecule nitrosamine and NDSRI formation pathways, highlighting key risk factors such as the role of excipients, pH, peroxides, and aldehydes. It also presents emerging control strategies – including the use of scavengers, pH modifiers, and process optimisation – supported by examples from recent product recall investigations.
2. Evaluating drug-drug interactions – a framework from lab to clinic
Our on-demand webinar help participants to recognise the clinical impact of drug–drug interactions and their contribution to adverse outcomes, as well as to understand how complementary methods can combine to ensure robust evaluation. Led by Professor Tore B. Stage, Head of Research at the University of Southern Denmark, the webinar also features a case study into isoxazolyl penicillins - with transferable insights that viewers will be able to apply to their own work.
Explore our year in numbers:
3. AXIO Proficiency Testing - The Essential Handbook
Bringing together some of AXIO’s most fundamental whitepapers in one place, this handbook distils some of the key insights that our scientists have gleaned from over 40 years’ experience in proficiency testing (PT). Among the subjects covered are Internal vs External PT, how effective PT can help prevent food product recalls, and the most common reasons for unsatisfactory PT performance.
LGC Standards – trusted science tools for a changing world
We are a leading global manufacturer and service provider in the analytical testing, quality assurance, and research tools sectors. Our 160,000+ products are critical tools in more than 170 countries, for scientists working in the pharmaceutical, healthcare, food, beverage, environmental and industrial market segments.
Trusted brands from LGC Standards include Dr Ehrenstorfer, AXIO Proficiency Testing, Mikromol, TRC, Lipomed, and LGC Industrial. Together, they provide laboratories with reference materials, analytical standards, research tools, and proficiency testing schemes that are produced to the highest specifications - including International Standards Organisation (ISO) and International Electrotechnical Commission (IEC) 17025 and 17034 guidelines.
As regulatory demands accelerate and testing laboratories face increasing analytical complexity, our expert scientists constantly innovate in order to ensure the continued safety and integrity of products and services worldwide. This continuous quest for improvement enabled us to release 2,000 novel products in 2025 – including 11 new 13C SILs for PFAS analysis, a groundbreaking range of 24 microplastic reference materials, 21 new API reference materials, and more than 30 new PT samples expertly designed to drive improvements in your laboratory testing.
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4. Identifying Testing Failures and Improving Laboratory Performance with LGC AXIO Proficiency Testing and PORTAL
This popular webinar explores the reasons why laboratories fail proficiency testing, how to prevent failures, and how to turn challenges into improvements. It’s presented by AXIO’s Head of Technical Operations, Dr Matthew Whetton, and Head of Data Management and Reporting, Richard Loftus.
5. Optimising PFAS Reference Material Design for use with Liquid Chromatography–High Resolution Accurate Mass Spectrometry (whitepaper), and PFAS Reference Material Optimisation (webinar)
Our readers liked our PFAS Reference Material Optimisation whitepaper so much, they also watched the webinar! Both top picks among scientists, these complementary thought leadership offerings are based on original research from a team led by LGC Standards’ Technical Director, Americas, Dr Dan Biggerstaff. They cover the importance of understanding how different PFAS analytes in reference materials and sample vials react to solvents and surface interactions, plus response factors and other parameters that impact data integrity amongst analytes in EPA Method 1633, UCMR 5 and EU DWD.
Authors
Andy Blizzard
Content Writer
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