(r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4 -yl]propionic Acid Sesquihydrate
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- structure.search.product.name (r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4 -yl]propionic Acid Sesquihydrate
- Product Code: TRC-A603150
- CAS Number: 209977-56-0
- Brand: TRC
Product Overview
Product Code
TRC-A603150
CAS Number
Product Format
Neat
Molecular Formula
2 C9 H12 N2 O6 . 3 H2 O
Molecular Weight
542.45
Product Categories
Glutamate receptors, TRC, Addiction, Neurotransmission, Alzheimer's, Depression, Huntington's, Epilepsy, Memory, Learning and Cognition, Multiple Sclerosis, Parkinson's, Schizophrenia, Stress and Anxiety, Stroke, Pain and Inflammation, API Reference Standards & Research Materials
Product Type
APIProduct Information
Chemical Data
Analyte Name
(r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4 -yl]
CAS Number
209977-56-0
Molecular Formula
2 C9 H12 N2 O6 . 3 H2 O
Molecular Weight
542.45
Accurate Mass
542.1708
SMILES
O.O.O.Cc1onc(OCC(=O)O)c1CC(N)C(=O)O.Cc2onc(OCC(=O)O)c2CC(N)C(=O)O
InChI
InChI=1S/2C9H12N2O6.3H2O/c2*1-4-5(2-6(10)9(14)15)8(11-17-4)16-3-7(12)13;;;/h2*6H,2-3,10H2,1H3,(H,12,13)(H,14,15);3*1H2
IUPAC
2-amino-3-[3-(carboxymethoxy)-5-methyl-1,2-oxazol-4-yl]propanoic acid;trihydrate
Product Data
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Type
API
Product Format
Neat
Product Description
A selective inhibitor of [3H]-AMPA binding in rat brain membranes. AMOA shows little affinity for [3H]-kainate binding sites or other sites on the NMDA receptor-channel complex, as represented by binding of [3H]-CPP, [3H]-gly or [3H]-MK-801. AMOA also selectively antagonizes AMPA-induced responses in rat cortical wedge preparations relative to kainate-, quisqualate- and NMDA-induced responses.
References: Frandsden, A., et al.: J. Neurochem., 55, 1821 (1990), Krogsgaard-Larsen, P., et al.: J. Med. Chem., 34, 123 (1991), Berg, M., et al.: Acta Neuropathalogica, 81, 255 (1991)
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