5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside
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Product Overview
Product Code
TRC-A611700
CAS Number
Product Format
Neat
Molecular Formula
C9 H14 N4 O5
Molecular Weight
258.23
API Family
AcadesineProduct Categories
TRC - Toronto Research Chemicals, Stable Isotope Labelled Analytical Standards, Stable Isotope Labelled Reference Materials, Nucleotides & nucleosides, Adenosine receptors, Huntington's, Parkinson's, Sleep, Stroke, Nucleoside chemistry, Nucleobase, nucleoside & nucleotide derivatives, Nucleotides and nucleosides, Neurology Research Chemicals and Analytical Standards, Cardiac drugs and beta blockers
Product Type
Bioactive Small MoleculePurity
>95% (HPLC)
Documentation
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Product Information
Chemical Data
Analyte Name
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside
CAS Number
2627-69-2
Molecular Formula
C9 H14 N4 O5
Molecular Weight
258.23
Accurate Mass
258.0964
Flash Point
-20
SMILES
NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1N
InChI
InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1
IUPAC
5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazole-4-carboxamide
Product Data
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Type
Bioactive Small Molecule
Product Format
Neat
API Family
Purity
>95% (HPLC)
Product Description
AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
References: Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)
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