text.skipToContent text.skipToNavigation

{{ addToCartData.mixPtRmWarning }}

Do you want to proceed?

{{requestQuote.productName}}; {{requestQuote.displayProductCode}}

Thank you

We will respond to your enquiry shortly.

Something went wrong, please try again later.

Quick Order
If not, click 'cancel'. You can also save this item for later.
Cancel

Sign in to view your unique pricing agreement and check out

{{ favouriteItem.successMessage }}

View favourites

Product removed from your favourites

{{ addToCartData.mixPtRmWarning }}

Do you want to proceed?

{{requestQuote.productName}}; {{requestQuote.displayProductCode}}

Thank you

We will respond to your enquiry shortly.

Something went wrong, please try again later.

Product Overview

Product Code

TRC-A617370

CAS Number

916603-07-1

Product Format

Neat

Molecular Formula

C17 H16 F N5

Molecular Weight

309.34

Product Categories

TRC, Kinase Inhibitors

Product Information

A novel enzyme-interacting compound using immobilised broad-spectrum ligands. An aminopyrimidine which is a pan-kinase inhibitor that binds to a range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES, which can be coupled to sepharose via its amino-side chain for affinity chromatography applications. This molecule has been identified as a useful target for kinase inhibitors.

 

References
[1] Klutchko, S.R., et al.: J. Med. Chem., 41, 3276 (1998).

Analyte Name

N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine

CAS Number

916603-07-1

Molecular Formula

C17 H16 F N5

Molecular Weight

309.34

Accurate Mass

309.139

SMILES

NCc1ccc(Nc2ncc(F)c(Nc3ccccc3)n2)cc1

InChI

InChI=1S/C17H16FN5/c18-15-11-20-17(22-14-8-6-12(10-19)7-9-14)23-16(15)21-13-4-2-1-3-5-13/h1-9,11H,10,19H2,(H2,20,21,22,23)

IUPAC

2-N-[4-(aminomethyl)phenyl]-5-fluoro-4-N-phenylpyrimidine-2,4-diamine

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Punchout session timeout warning

Your punchout session will expire in 1 min 59 sec.

Select "Continue session" to extend your session.