Diphenyleneiodonium Chloride
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Product Overview
Product Code
TRC-D491500
CAS Number
Product Format
Neat
Molecular Formula
C12 H8 I . Cl
Molecular Weight
314.55
Product Categories
TRC, Enzyme inhibitors, Additional Neuro Products, Pain and Inflammation, Neurology Research Chemicals and Analytical Standards
Product Type
Bioactive Small MoleculePurity
>95% (HPLC)
Documentation
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Product Information
Chemical Data
Analyte Name
Diphenyleneiodonium Chloride
CAS Number
4673-26-1
Molecular Formula
C12 H8 I . Cl
Molecular Weight
314.55
Accurate Mass
313.9359
SMILES
[Cl-].c1ccc2c(c1)[i+]c3ccccc23
InChI
InChI=1S/C12H8I.ClH/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11;/h1-8H;1H/q+1;/p-1
Product Data
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Format
Neat
Purity
>95% (HPLC)
Product Description
Diphenyleneiodonium Chloride binds strongly to flavoproteins and thus inhibits NO synthase, NADG reductase and NADPH oxidase.Diphenyleneiodonium Chloride solubility: 5 mg in 1.7 mL of H2O:DMSO 40:60; 10 mg in 1.1 mL H2O:DMSO 10:90
References: Jones, et al.: Biochem J., 265, 95 (1990), Stuehr, et al.: FASEB J., 5, 98 (1991), Wang, Y-X, et al.: J. of Pharmacology & Exp. Therap., 265, 1 , 263 (1993) Circulation Research, 74 (6), 1142 (1994), Cruz, T.F., et al.: J.B.C., 271, 26, 15703(1996)