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Product Overview

Product Code

TRC-P700745

CAS Number

104632-27-1

EP Description

Pramipexole EP Impurity D

USP Description

Pramipexole USP Related Compound D

Product Format

Neat

Molecular Formula

C10 H17 N3 S . 2 Cl H

Molecular Weight

284.25

API Family

Pramipexole

Product Categories

TRC, Impurity Reference Materials , API Reference Standards & Research Materials

Product Type

API

Alternate CAS Number

Free base: 104632-28-2

Documentation

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Product Information

Chemical Data

Analyte Name

(R)-Pramipexole-Dihydrochloride

CAS Number

104632-27-1

Molecular Formula

C10 H17 N3 S . 2 Cl H

Molecular Weight

284.25

Accurate Mass

283.0677

SMILES

NC1=NC(CC[C@](N)(CCC)C2)=C2S1.[H]Cl.[H]Cl

InChI

InChI=1S/C10H17N3S.2ClH/c1-2-4-10(12)5-3-7-8(6-10)14-9(11)13-7;;/h2-6,12H2,1H3,(H2,11,13);2*1H/t10-;;/m1../s1

IUPAC

(6R)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine;dihydrochloride

Alternate CAS Number

Free base: 104632-28-2

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

API Family

Pramipexole

Product Description

(R)-Pramipexole Dihydrochloride (Pramipexole EP Impurity D; Pramipexole BP Impurity D; Pramipexole USP Related Compound D) is the opposite enantiomer of Pramipexole (P700755), a dopamine-D2-receptor agonist. Dexpramipexole is a low-molecular-weight, water-soluble, orally bioavailable, renally excreted compound with linear pharmacokinetics.

References: Mierau, J., et al.: J. Med. Chem., 30, 494 (1987), Schilling, J.C., et al.: Clin. Pharmacol. Ther., 51, 541 (1992), Kieburtz, K., et al.: J. Am. Med. Assoc., 278, 125 (1997)

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