Product Code

TRC-S692060

CAS Number

51568-18-4

Product Format

Neat

Molecular Formula

C7 H10 O4

Molecular Weight

158.1519

Product Categories

TRC, Carbohydrate derivatives, Additional pharmaceutical toxicology research materials

Price and availability

48-hour USA dispatch time

Freight restricted.

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Product Information

Chemical Data

Analyte Name

Succinylacetone

CAS Number

51568-18-4

Molecular Formula

C7 H10 O4

Molecular Weight

158.1519

Accurate Mass

158.0579

SMILES

CC(=O)CC(=O)CCC(=O)O

InChI

InChI=1S/C7H10O4/c1-5(8)4-6(9)2-3-7(10)11/h2-4H2,1H3,(H,10,11)

IUPAC

4,6-dioxoheptanoic acid

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Product Description

Succinylacetone (SA) is a specific marker for the inherited metabolic disease, hepatorenal tyrosinemia. It was developed a stable-isotope for the determination of SA in dried blood spots (DBS) and liquid urine using a 13C4-SA as internal standard. The method was applied retrospectively and prospectively for the diagnosis of hepatorenal tyrosinemia and for follow-up of patients under treatment.

References: Kvittingen, E., et al.: Inher. Metab. Dis., 14, 554 (1991), Lindstedt, S., et al.: Lancet, 340, 813

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