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Product Overview

产品代码

TRC-B387050

CAS登记号

130641-38-2

产品形式

Neat

分子式

C19 H20 N2 O3

分子量

324.374

产品类型

TRC

产品信息

分析物名称

Bindarit

CAS登记号

130641-38-2

分子式

C19 H20 N2 O3

分子量

324.374

精确质量测定

324.147

SMILES

CC(C)(OCc1nn(Cc2ccccc2)c3ccccc13)C(=O)O

InChI

InChI=1S/C19H20N2O3/c1-19(2,18(22)23)24-13-16-15-10-6-7-11-17(15)21(20-16)12-14-8-4-3-5-9-14/h3-11H,12-13H2,1-2H3,(H,22,23)

IUPAC

2-[(1-benzylindazol-3-yl)methoxy]-2-methylpropanoic acid

运输温度

Room Temperature

原产国

CANADA

产品类型

Bioactive Small Molecule

产品形式

Neat

Bindarit shows anti-inflammatory activity due to a selective inhibition of a subfamily of inflammatory chemokines. Bindarit is a also protein antidenaturant agent. Bindarit modulates the NFkB pathway and has been shown to reduce secondary phase of adjuvant arthritis in rats.

References: Mora, E. et al.: Call Cycle, 11, 169 (2012); Cioli, V. et al.: J. Rheumatol., 19, 1735 (1992); Guglielmotti, A. et al.: Inflam. Res., 51, 252 (2002); Grassia, G. et al.: Cardio. Res., 84, 485 (2009);

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