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Product Overview

产品代码

TRC-A617370

CAS登记号

916603-07-1

产品形式

Neat

分子式

C17 H16 F N5

分子量

309.34

产品类型

TRC, Kinase Inhibitors

产品信息

A novel enzyme-interacting compound using immobilised broad-spectrum ligands. An aminopyrimidine which is a pan-kinase inhibitor that binds to a range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES, which can be coupled to sepharose via its amino-side chain for affinity chromatography applications. This molecule has been identified as a useful target for kinase inhibitors.

 

References
[1] Klutchko, S.R., et al.: J. Med. Chem., 41, 3276 (1998).

分析物名称

N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine

CAS登记号

916603-07-1

分子式

C17 H16 F N5

分子量

309.34

精确质量测定

309.139

SMILES

NCc1ccc(Nc2ncc(F)c(Nc3ccccc3)n2)cc1

InChI

InChI=1S/C17H16FN5/c18-15-11-20-17(22-14-8-6-12(10-19)7-9-14)23-16(15)21-13-4-2-1-3-5-13/h1-9,11H,10,19H2,(H2,20,21,22,23)

IUPAC

2-N-[4-(aminomethyl)phenyl]-5-fluoro-4-N-phenylpyrimidine-2,4-diamine

运输温度

Room Temperature

原产国

CANADA

产品形式

Neat

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