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Product Overview

Product Code

TRC-A796002

Product Format

Neat

Molecular Formula

C8H1215N4O5

Molecular Weight

248.18

Product Categories

TRC, Oligosaccharides, Carbohydrates, Enzyme inhibitors, Stable isotopes, Stable Isotope Labelled Analytical Standards, Cancer Research Chemicals and Analytical Standards

Product Type

Stable Isotope Labelled

Unlabelled CAS Number

320-67-2

Purity

>95% (HPLC)

Documentation

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Product Information

Chemical Data

Analyte Name

5-Azacytidine-15N4

Molecular Formula

C8H1215N4O5

Molecular Weight

248.18

SMILES

O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1[15N]2C([15N]=C([15NH2])[15N]=C2)=O

InChI

InChI=1S/C8H13N4O8P/c9-7-10-2-12(8(15)11-7)6-5(14)4(13)3(20-6)1-19-21(16,17)18/h2-6,13-14H,1H2,(H2,9,11,15)(H2,16,17,18)/t3-,4-,5-,6-/m1/s1

IUPAC

[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

Unlabelled CAS Number

320-67-2

SIL Type

Nitrogen

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Type

Stable Isotope Labelled

Product Format

Neat

Purity

>95% (HPLC)

Product Description

Labelled Azacytidine (A796000), a potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase.

References: Kusaba, H., et al.: Eur. J. Biochem., 262, 924 (1999), Broday, L., et al.: Mol. Cell Biol., 19, 3198 (1999), Qian, X., et al.: Am. J. Pathol., 153, 1475 (1999), Canova, C., et al.: Mech. Ageing Dev., 101, 153 (1998)

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