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Product Overview

Product Code

TRC-I819500

CAS Number

359436-55-8

Product Format

Neat

Molecular Formula

C10 H13 N5 O5 . H2 O

Molecular Weight

301.26

API Family

Regadenoson

Product Type

API

Alternate CAS Number

Anhydrous: 1818-71-9

Documentation

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Product Information

Analyte Name

Isoguanosine Hydrate

CAS Number

359436-55-8

Molecular Formula

C10 H13 N5 O5 . H2 O

Molecular Weight

301.26

Accurate Mass

301.1022

SMILES

O.NC1=NC(=O)Nc2c1ncn2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O

InChI

InChI=1S/C10H13N5O5.H2O/c11-7-4-8(14-10(19)13-7)15(2-12-4)9-6(18)5(17)3(1-16)20-9;/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19);1H2/t3-,5-,6-,9-;/m1./s1

IUPAC

6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-2-one;hydrate

Alternate CAS Number

Anhydrous: 1818-71-9

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Type

API

Product Format

Neat

API Family

Regadenoson

A useful synthetic intermedate. A naturally occuring, biologically active isomer of guanosine. Reported to stimulate the accumulation of cyclic-AMP in the brain. It is an inhibitor of IMP pyrophosphorylase, and its 5???-di and -tri-phosphates inhibit glutamic acid dehydrogenase. May contain approximately 0.6 moles of water.

References: Divakar, K.J., et al.: J. Chem. Soc. Perkin Trans., 1, 771 (1991), Montsch, H.H., et al: Biochemistry, 14, 5593 (1975), Hagen, C.: Biochim. Biophys. Acta., 293, 105 (1973), Huang, M., et al.: J. Med. Chem., 15, 462 (1972)

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