Name: N-Biotinylaminoethyl Methanethiosulfonate
Brand: TRC
SKU: TRC-B394750

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Product Overview

Product Code

TRC-B394750

CAS Number

162758-04-5

Product Format

Neat

Molecular Formula

C13 H23 N3 O4 S3

Molecular Weight

381.53

Product Categories

TRC, Cross-Linkers, Serotonin, 5-HT receptors, Neurotransmission, Alzheimer's, Memory, Learning and Cognition, Parkinson's, Addiction, Schizophrenia, Pain and Inflammation

Product Type

Bioactive Small Molecule

Documentation

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Product Information

Chemical Data

Analyte Name

N-Biotinylaminoethyl Methanethiosulfonate

CAS Number

162758-04-5

Molecular Formula

C13 H23 N3 O4 S3

Molecular Weight

381.53

Accurate Mass

381.0851

SMILES

CS(=O)(=O)SCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12

InChI

InChI=1S/C13H23N3O4S3/c1-23(19,20)22-7-6-14-11(17)5-3-2-4-10-12-9(8-21-10)15-13(18)16-12/h9-10,12H,2-8H2,1H3,(H,14,17)(H2,15,16,18)/t9-,10-,12-/m0/s1

IUPAC

5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-(2-methylsulfonylsulfanylethyl)pentanamide

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Type

Bioactive Small Molecule

Product Format

Neat

Product Description

Reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease. MTSEA-biotin has recently been used to probe the topology of the serotonin (5-HT) transporter by site-directed chemical labelling.

References: J. Biol. Chem., 273(20), 12675 (1998), Adams, C.M., et al.: J. Biol. Chem., 273 (46), 30204 (1998), Boileau, A. J., et al.: J. Neurosci., 19, 12, 4847 (1999), Wagner, D.A.and Czajkowski, C.: J. Neurosci., 21, 67 (2001), Traebert, M.: J. Membr. Biol., 180, 83 (2001)

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