PD-166866
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- structure.search.product.name PD-166866
- Product Code: TRC-P217550
- CAS Number: 192705-79-6
- Brand: TRC
Product Overview
Product Code
TRC-P217550
CAS Number
Product Format
Neat
Molecular Formula
C20 H24 N6 O3
Molecular Weight
396.44
Product Categories
TRC, Approved therapeutics/drug candidates, Kinase Modulators, Cytokine and Growth Factor Signalling Modulators
Product Type
Bioactive Small MoleculeDocumentation
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Product Information
Chemical Data
Analyte Name
PD 166866
CAS Number
192705-79-6
Molecular Formula
C20 H24 N6 O3
Molecular Weight
396.44
Accurate Mass
396.191
SMILES
COc1cc(OC)cc(c1)c2cc3cnc(N)nc3nc2NC(=O)NC(C)(C)C
InChI
InChI=1S/C20H24N6O3/c1-20(2,3)26-19(27)25-17-15(8-12-10-22-18(21)24-16(12)23-17)11-6-13(28-4)9-14(7-11)29-5/h6-10H,1-5H3,(H4,21,22,23,24,25,26,27)
IUPAC
1-[2-amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
Product Data
Storage Temperature
+4°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Type
Bioactive Small Molecule
Product Format
Neat
Product Description
A novel potent ATP competitive pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors. An inhibitor of the basic fibroplast growth factor (bFGF).
References: Zhu, X., et al.: Science, 251, 90 (1991), Davies, D.E., et al.: Biochem. Pharmacol., 51, 1101 (1996), Panek, R.L., et al.: J. Pharmacol. Exp. Ther., 286, 569 (1998), Iacoangeli, A., et al.: Biochimie, 82, 35 (2000),
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