4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
Share product
- structure.search.product.name 4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
- Product Code: TRC-B285725
- CAS Number: 327036-89-5
- Brand: TRC
Product Overview
Product Code
TRC-B285725
CAS Number
Product Format
Neat
Molecular Formula
C10 H10 N2 O2 S
Molecular Weight
222.26
Product Categories
Additional Neuro Products, TRC, Chiral catalysts, ligands, & reagents
Product Type
Synthesis ToolsDocumentation
Find an SDS for your region
{{ errors[0] }}
{{ errors[0] }}
For information about our data processing activities, please visit our Privacy Notice.
Your request has been sent to our sales team to process.
Product Information
Chemical Data
Analyte Name
4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
CAS Number
327036-89-5
Molecular Formula
C10 H10 N2 O2 S
Molecular Weight
222.26
Accurate Mass
222.0463
SMILES
CN1SC(=O)N(Cc2ccccc2)C1=O
InChI
InChI=1S/C10H10N2O2S/c1-11-9(13)12(10(14)15-11)7-8-5-3-2-4-6-8/h2-6H,7H2,1H3
IUPAC
4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
Product Data
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Type
Synthesis Tools
Product Format
Neat
Product Description
Glycogen Synthase Kinase-3ß is a highly conserved ubiquitously expressed serine/threonine protein kinase involved in signal transduction cascades of multiple cellular processes. TDZD-8 is a thiadiazolidinone (TDZD) analogue that acts as a highly selective, non-ATP competitive inhibitor of GSK-3ß ( IC50 =2nM). Binds to the active site of GSK-3ß. Does not significantly affect the activities of Cdk-1/cyclin B, CK-II, PKA, and PKC (IC50 >100nM).
References: Martinez, A., et al.: J. Med. Chem., 45, 1292 (2002)
{{title}}
Please login or register to add to your favourites
Or continue browsing without access to favourites or pricing
Please log in to view pricing and add to cart
Or continue browsing to see available rounds without pricing information
If you don't yet have an account, please create an account create an account
-
Product Code:
{{ isMultiplePacksize(product) ? getSourcePart(product) : product.code }} {{ isMultiplePacksize(product) ? getSourcePart(product) : product.code }}
Controlled product
Login to view full product details
{{ addToCartData.mixPtRmWarning }}
Do you want to proceed?
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}
{{ errors[0] }}