N-Succinimidoxycarbonyl-Beta-alanine N-Succinimidyl Ester 1,4- Dioxane complex
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- structure.search.product.name N-Succinimidoxycarbonyl-Beta-alanine N-Succinimidyl Ester 1,4- Dioxane complex
- Product Code: TRC-S689850
- CAS Number: 1215667-16-5
- Brand: TRC
Product Overview
Product Code
TRC-S689850
CAS Number
Product Format
Neat
Molecular Formula
C12 H13 N3 O8 . C4 H8 O2
Molecular Weight
415.35
Product Categories
Product Type
APIDocumentation
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Product Information
Chemical Data
Analyte Name
N-Succinimidoxycarbonyl-beta-alanine N-Succinimidyl Ester, 1,4-Dioxane
CAS Number
1215667-16-5
Molecular Formula
C12 H13 N3 O8 . C4 H8 O2
Molecular Weight
415.35
Accurate Mass
415.1227
SMILES
O=C(CCNC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O.C3COCCO3
InChI
InChI=1S/C12H13N3O8.C4H8O2/c16-7-1-2-8(17)14(7)22-11(20)5-6-13-12(21)23-15-9(18)3-4-10(15)19;1-2-6-4-3-5-1/h1-6H2,(H,13,21);1-4H2
IUPAC
1,4-dioxane;(2,5-dioxopyrrolidin-1-yl) 3-[(2,5-dioxopyrrolidin-1-yl)oxycarbonylamino]propanoate
Product Data
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Type
API
Product Format
Neat
Product Description
A short, amino reactive homobifunctional crosslinking reagent. Crosslinking distance 8.3 +?. It is useful in polymer coupling to proteins, because it may lead to a better selectivity among all the amino groups present in a protein, thus yielding less heterogeneous PEG-protein conjugates mixture because only the most nucleophilic and solvent exposed amines can react.
References: Gross, H., et al.: Tetrahedron, 24, 6935 (1968), Clark, R., et al.: J. Biol. Chem., 271, 21969 (1996), Guiotto, A., et al.: Bioorg. Med. Chem., 12, 5031 (2004),
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