Name: D-erythro-Sphingosine-1-phosphate-13C2,D2
Brand: TRC
SKU: TRC-S681502

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Product Overview

Product Code

TRC-S681502

Product Format

Neat

Molecular Formula

C1613C2H36D2NO5P

Molecular Weight

383.47

Product Categories

TRC, Enzyme inhibitors, Glycerolipids, Glycerophospholipids, Lipids & fatty acids, Glycerolipids, Glycerophospholipids, Lipids & fatty acids, Kinase Modulators, Stable isotopes, Kinase C, Memory, Learning and Cognition, Stable isotopes, Stable Isotope Labelled Analytical Standards

Product Type

Stable Isotope Labelled

Unlabelled CAS Number

26993-30-6

Documentation

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Product Information

Chemical Data

Analyte Name

D-erythro-Sphingosine-1-phosphate-13C2,D2

Molecular Formula

C1613C2H36D2NO5P

Molecular Weight

383.47

SMILES

N[13C@]([C@H](O)/C=C/CCCCCCCCCCCCC)([H])[13C]([2H])([2H])OP(O)(O)=O

InChI

InChI=1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+/t17-,18-/m1/s1/i16+1D2,17+1

Unlabelled CAS Number

26993-30-6

SIL Type

Deuterium, Carbon

Product Data

Storage Temperature

-20°C

Shipping Temperature

Blue Ice

Country of Origin

CANADA

Product Type

Stable Isotope Labelled

Product Format

Neat

Product Description

A labelled putative lipid second messenger; found to inhibit cellular mobility of melanoma cells at very low concentrations with no toxic effects thereby making it a possible agent for prevention of tumor cell metastasis and inflammatory processes; mobilizes intracellular calcium stores; decreases cellular cAMP; activates phospholipase D; does not inhibitprotein kinase C.

References: Zhang, H., et al.: J. Cell Biol., 114, 155 (1991) Sadahira, Y., et al.: Proc. Natl. Acad. Sci. USA (1992), Cuvillier, O., et al.: Nature, 381, 800 (1996)

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