TIQ-A
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- structure.search.product.name TIQ-A
- Product Code: TRC-T445100-1MG
- CAS Number: 420849-22-5
- Brand: TRC
Product Overview
Product Code
TRC-T445100-1MG
CAS Number
Product Format
Neat
Molecular Formula
C11 H7 N O S
Molecular Weight
201.24
Product Categories
Product Type
Bioactive Small MoleculeDocumentation
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Product Information
Chemical Data
Analyte Name
TIQ-A
CAS Number
420849-22-5
Molecular Formula
C11 H7 N O S
Molecular Weight
201.24
Accurate Mass
201.0248
SMILES
O=C1Nc2sccc2c3ccccc13
InChI
InChI=1S/C11H7NOS/c13-10-8-4-2-1-3-7(8)9-5-6-14-11(9)12-10/h1-6H,(H,12,13)
IUPAC
4H-thieno[2,3-c]isoquinolin-5-one
Product Data
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Type
Bioactive Small Molecule
Product Format
Neat
Product Description
A cell permeable, potent PARP inhibitor with an IC50 of 450nM. Shown to be neuroprotective against oxygen-glucose deprivation injury in vitro in cultured murine cortical cells ( IC50 of 150nM) and in vivi in rat transient focal ischemia model (3 mg/kg ip).
References: Chiarugi, A., et al.: J. Pharmacol. Exp. Ther., 305, 43 (2003), pellicciari, R., et al.: Farmaco., 58, 851 (2003)
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